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A Detox From Xanax A detoxification of Xanax allows the body to get rid of Xanax without withdrawal symptoms. However, when one fails to take Xanax for a while, or even when one takes a reduced amount from what one is supposed to take, one experiences withdrawal symptoms. The symptoms of withdrawal at first are not much, but these include anxiety, irritability, sweating, headaches, tremors, shakiness, dizziness, muscle aches, fatigue, insomnia, palpitations, and concentration and memory problems.